The Seizure and Cognitive Outcome of Anterior Thalamic Nucleus Deep Brain Stimulation for Patients with Intractable Epilepsy
نویسندگان
چکیده
10.4172/Neuropsychiatry.1000S1001 © 2017 pISSN 1758-2008 eISSN 1758-2016 Neuropsychiatry (London) (2017) S(1), 04–09 4 1Department of Neurosurgery, SanBo Brain Hospital, Capital Medical University, 10093, Beijing, China 2Department of Neurology, SanBo Brain Hospital, Capital Medical University, 10093, Beijing, China 3Beijing Key Laboratory of Epilepsy, 100093, Beijing, China 4Center of Epilepsy, Beijing Institute for Brain Disorder’s, 10093, Beijing, China †Author for correspondence: Guoming Luan, Department of Neurosurgery, Beijing Sanbo Brain Hospital, Capital Medical University, Beijing, 100093, China. Tel: 86-10-62856718, Fax: 86-10-62856902, email: [email protected]
منابع مشابه
Cognitive improvement after long-term electrical stimulation of bilateral anterior thalamic nucleus in refractory epilepsy patients
INTRODUCTION The cognitive and behavioral effect of deep brain stimulation (DBS) administered to the deep cerebral nuclei for epilepsy treatment is unknown. We investigated the cognitive outcomes at least 12 months after DBS to the bilateral anterior thalamic nucleus (ATN) for controlling intractable epilepsy. METHODS Nine patients with intractable epilepsy who were not candidates for resecti...
متن کاملControl of epileptic seizures by electrical low frequency deep brain stimulation: A review of probable mechanisms
Epilepsy is the most common neurological disease with no definitive method in treatment. Notably, the main way to treat and control epileptic seizures is drug therapy. However, about 20-30% of patients with epilepsy are drug resistant and require other therapeutic manners. Deep brain stimulation is a new therapeutic strategy for these patients. Conspicuously, there are no clear answers for basi...
متن کاملLong-term anterior thalamus stimulation for intractable epilepsy.
BACKGROUND Deep brain stimulation (DBS) has re-emerged as an alternative therapy for intractable epilepsy. In this study, we investigated the feasibility, efficacy and safety of long-term anterior thalamic nucleus (ATN) stimulation for intractable epilepsy. METHODS In this open-label pilot study of electrical stimulation of the ATN, we investigated four cases of intractable epilepsy (one man ...
متن کاملRapid Eye Movement Sleep: A Predictive Marker of Success and Efficacy of Deep Brain Stimulation in Intractable Epilepsy
Deep brain stimulation (DBS) is progressively establishing as an alternative therapy in various neurological disorders not amenable satisfactorily to medication. In IE also, DBS of anterior thalamic nucleus (ATNDBS) has been approved by FDA and several studies have reported its success and efficacy including the randomized SANTE trials [1]. As is common with any therapeutic strategy, ATNDBS als...
متن کاملNeurostimulation. A promising therapeutic option for medically refractory epilepsy.
Epilepsy is a common and serious chronic neurological disorder, affecting around 65 million people worldwide. Despite the advances in pharmacologic treatments for epilepsy, approximately 30% of the patients remain medically refractory and continue to have seizures on medications, in such cases, other treatment approaches are necessary. Resection surgery can be an alternative in many patients to...
متن کامل